Los Angeles County
County data1,824
CDC's provisional county-level data count 1,824 drug overdose deaths among residents of Los Angeles County, home to Los Angeles, in the 12 months ending December 2025.
12 months ending December 2025
Previous period1,82912 months ending December 2024
The Los Angeles County figure is about level with 1,829 in the 12 months ending December 2024.
Los Angeles
City population3.87 million
Los Angeles has about 3.87 million residents (3,869,089 in the Census Bureau's July 1, 2025 estimate), the 2nd-largest city in the country. It ranks as the largest incorporated place in California, though it lost residents from 3,896,473 in the 2020 estimate, and is home to about 10% of California's 39.4 million residents.
California
State data8,373
Across California, which includes Los Angeles, CDC provisional data count 8,373 overdose deaths in the 12 months ending April 2026, a provisional figure CDC flags as underreported because some records are still incomplete.